To win something easily or decisively.
Hindi meaning:आसानी से जीतना
Synonyms: Prevail, Conquer, Trounce, Annihilate
Antonyms: Yield, Lose, Surrender
Example: We were really unprepared for our last game, and the other team won hands down.
Trick to remember: Ye kal ki win Win hands down nhi thi.